The MISTRAL™ column thermostat offers precise and stable temperature control ranging from 5ºC up to 90ºC to bring even your most demanding separation under control. The forced-air concept allows easy access to the column(s) and offers maximum flexibility with respect to column dimensions.
Why do you have to thermostat the column?
Every separation is a function of temperature and stable retention times can only be guaranteed if the column temperature is not influenced by ambient temperature fluctuations. Obviously, temperature control will also help to comply with GLP requirements. Column back-pressure reduction may be needed if you want to speed up your HPLC analysis and a simple increase in temperature will do the job. The MISTRAL™ column thermostat offers precise and stable temperature control ranging from 5ºC up to 90ºC to bring even your most demanding separation under control. The forced-air concept allows easy access to the column(s) and offers maximum flexibility with respect to column dimensions. Many chiral separations require sub-ambient temperatures for sufficient resolution and many ion-exchange separations are efficient only at elevated temperatures.
Forced air heat-exchange is the most convenient way to control the column temperature. In contrast to heater blocks you have maximum freedom for column dimensions and unlike water jackets you have easy access to the column. Multiple columns are possible and even the injection valve can be mounted in the thermostat! Forced air is convenient, but GC technology has learnt that heat exchange is only efficient if you blow hard. Like the powerful cold “Mistral” winds that occasionally blow in the Rhone valley in France, the MISTRAL™ fan blows hard for proper heat exchange!
Stable and Safe
The selected column temperature is maintained within as little as +/- 0.1°C to guarantee maximum precision of retention times. The large area heating/cooling elements provide excellent temperature distribution and avoid hazardous “hot spots”. In addition, a vapor alarm will alert you in case of solvent leakage in the thermostat. Comforting features when the emphasis is on stable and safe performance.
Peltier Technology for Full Range Control
The MISTRAL™ with Peltier cooling has an extended temperature range from 5°C up to 90°C. Integrated cooling by Peltier elements is most convenient, because it does not require an external cooling device and it accelerates cooling-down and warming-up!
Compatible with any HPLC system
The MISTRAL™ will fit in any HPLC system and flexible positioning of inlet and outlet tubing allows short connections to most detectors and autosamplers. A manual injection valve fits in the door of the thermostat for optimum temperature control and minimum tubing length between column and injector. Remote control is possible via conventional I/O and via the serial RS 232 port using the SparkLink communication protocol.
- MistraSwitch: Provides automated column selection and unsupervised optimization of the separation. Includes control software which can be integrated with the following instrument control software:
- Agilent ChemStation; ABI Analyst V1.4.1; ChromSword (Merck)
- Dionex Chromeleon; Perkin Elmer Turbochrom/Totalchrom
- EZChrom Elite (Shimadzu, Merck-Hitachi, Knauer, Jasco (only for versions with EZChrom Basis) and others
- Manual Injector: Integrated manual injection valve
- Multiple Column Selection: The mechanical switching part is mounted inside the column oven compartment and allows to switch up to 6 columns
Column switching MistraSwitch